Student activities outside the classroom help the school to fulfill its mission to "challenge students spiritually, academically, physically, socially and aesthetically within the traditions and teachings of the Roman Catholic Church." While many student activities are offered outside of the school day, Delone Catholic also offers bimonthly activities periods during the school day, so that students for whom transportation is an issue can participate in the extracurricular life of the school. 

Delone Catholic offers the following clubs, teams and activities: